Smart drugs promote maximum mental performance in four basic ways. First, they supercharge the brain with an optimal supply of oxygen and the raw materials it needs to energize its neurons and store and recall memories. Second, they shield the brain against free-radical damage and other toxic substances that can lead to permanent brain damage. Third, they help remove cellular debris, called lipofuscin pigment (the same aging pigment that causes "liver spots" on the skin), from the brain, which has been linked to neuron damage and decreased mental performance. Fourth, they supply the brain with raw materials to replenish its supply of neurotransmitters.
Oxygen plays a Jekyll-Hyde role in the brain: It energizes the brain to think and remember more clearly while it ironically promotes free-radical damage that can lead to a host of neurological disorders, such as senility and stroke. Nootropic drugs play a unique role among all drugs in that they both optimize the delivery and use of oxygen to the brain and protect the brain from the hazards of oxygen-induced free radicals.
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